SPECIFIC PROMOTER OF THE HUMAN VASCULAR ENDOTHELIAL CADHERIN-2 (HVE-CAD-2) GENE AND THE THERAPEUTIC USES THEREOF

摘要

The invention relates to a nucleic acid fragment which contains the regulatory sequence of the VE-Cad-2- gene, a complete or a functional active variation thereof. The invention also relates to a nucleic acid construct containing the nucleic acid fragment and a functional nucleic acid sequence or a heterological gene, a vector or a vector system, a cell or a cell line, a transgenic non-human animal, a medicament, a diagnostic, an array, a method for identifying pharmaceutically active substances, a method for identifying functionally active variants, a method for isolating endothelium cells from stem cells, a method for treatment, a method for administering a medicament, the use of the nucleic acid fragment, the nucleic acid construct, the transformed cell or cell lines of the tests and the arrays.