发明名称 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR RELIABLE ACHIEVEMENT OF ACCEPTABLE SERUM TESTOSTERONE LEVELS |
摘要 |
The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician. |
申请公布号 |
WO2004080383(A2) |
申请公布日期 |
2004.09.23 |
申请号 |
WO2004IB00716 |
申请日期 |
2004.03.15 |
申请人 |
SCHERING AKTIENGESELLSCHAFT;HUEBLER, DORIS;FRICKE, SABINE;INGWERSEN, JAN-PETER;KUHNZ, WILHELM |
发明人 |
HUEBLER, DORIS;FRICKE, SABINE;INGWERSEN, JAN-PETER;KUHNZ, WILHELM |
分类号 |
A61K9/00;A61K31/56;A61K31/565;A61K31/568;A61K31/57;A61K36/47;A61K47/14;A61K47/44 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|