A COMPOSITION COMPRISING AN EXTRACT OF RHEI RHIZOMA OR PHYSCION COMPOUND ISOLATED THEREFROM FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION

摘要

A composition comprising the extract of Rhei Rhizoma or physcion compound isolated therefrom is provided to inhibit coagulation and toxicity of beta-amyloid and restore memory by promoting proliferation of nerve cells, so that the composition is useful for treating or preventing cognitive dysfunction. A composition for treating or preventing cognitive dysfunction comprises 0.1-50 wt.% of the extract of Rhei Rhizoma which is prepared by extracting with water, C1-C4 lower alcohol, acetone, diethylether, ethylacetate, chloroform or dichloromethane or physcion compound isolated therefrom, and is a pharmaceutical or health food composition having a formulation of tablet, capsule, pill or solution, wherein the cognitive dysfunction is Alzheimer type dementia, cerebrovascular dementia, Pick's disease, Creutzfeldt-jakob disease, dementia caused by brain damage or Parkinson's disease. Further, the Rhei Rhizoma or the physcion compound isolated therefrom is used as health function food for treating or preventing cognitive dysfunction.