<p>High molecular weight hyaluronic acid can be efficiently produced by incorporating one or more compounds having at least one aromatic ring to which one or more hydroxyl groups are attached into a medium for producing hyaluronic acid by a bacterium capable of producing hyaluronic acid. By using this method, a sufficient amount of hyaluronic acid can be easily obtained without decomposing the high molecular structure of hyaluronic acid so that the process for isolating and purifying hyaluronic acid from the medium can be simplified.</p>
申请公布号
EP0266578(A2)
申请公布日期
1988.05.11
申请号
EP19870114797
申请日期
1987.10.09
申请人
MITSUBISHI RAYON CO. LTD.
发明人
MIYAMORI, TAKAO C/O MITSUBISHI RAYON CO., LTD.;NUMAZAWA, RYOZO C/O MITSUBISHI RAYON CO., LTD.;SAKIMAE, AKIHIRO C/O MITSUBISHI RAYON CO., LTD.;ONISHI, HISAO C/O MITSUBISHI RAYON CO., LTD.