DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G-PROTEIN COUPLED RECEPTOR PROSTAGLANDIN E2 EP2 (PROSTAGLANDIN E2 EP2)

摘要

Diagnostics and Therapeutics for Diseases Associated with G-Protein Coupled Receptor Prostaglandin E2 EP2 (Prostaglandin E2 EP2)Abstract of DisclosureThe invention provides a human prostaglandin E2 EP2 which is associated with the cardiovascular diseases, hematological diseases, respiratory diseases, urological diseases, cancer and gastroenterological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, hematological diseases, respiratory diseases, urological diseases, cancer and gastroenterological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of prostaglandin E2 EP2 as well as pharmaceutical compositions comprising such compounds.