Extracorporeal removal of microvesicular particles

摘要

The invention described herein teaches methods of removing microvesicular particles, which include but are not limited to exosomes, from the systemic circulation of a subject in need thereof with the goal of reversing antigen-specific and antigen-nonspecific immune suppression. Said microvesicular particles could be generated by host cells that have been reprogrammed by neoplastic tissue, or the neoplastic tissue itself. Compositions of matter, medical devices, and novel utilities of existing medical devices are disclosed.

主权项

1. A method of capturing an exosome from a patient on a surface that comprises a lectin, said method comprising:
identifying a patient for exosome capture and contacting an exosome from said patient with a surface that comprises a lectin thereby capturing said exosome.