发明名称 PYRROLOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASE.
摘要 <p>The present invention relates to compounds of formula (I) wherein Q, Z, R<sup>1</sup> , R<sup>2</sup> , and R<sup>3</sup> are as described in claim 1 useful as inhibitors of protein kinases, particularly of JAK family and ROCK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.</p>
申请公布号 MX2007014619(A) 申请公布日期 2009.02.13
申请号 MX20070014619 申请日期 2006.05.22
申请人 VERTEX PHARMACEUTICALS INCORPORATED. 发明人 TIANSHENG WANG;JIAN WANG;GABRIEL MARTINEZ-BOTELLA;FRANCESCO G. SALITURO;MARK W. LEDEBOER;ALBERT C. PIERCE;GUY W. BEMIS;LUC J. FARMER;MARION W. WANNAMAKER;RANDY S. BETHIEL;MICHAEL J. ARNOST;JOHN H. COME
分类号 C07D471/04;A61K31/437;A61P35/00;C07D487/04 主分类号 C07D471/04
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