发明名称 |
SELECTION OF INTRACELLULAR IMMUNOGLOBULINS |
摘要 |
A general immunoglobulin-target assay system is provided, in which a positive outcome (the generation of a signal) depends only on the intracellular interaction of immunoglobulin with target. This can be accomplished for many immunoglobulins expressed in yeast and/or in mammalian cells and allows the selection of immunoglobulins which are capable of functioning in an intracellular environment. |
申请公布号 |
EP1166121(A1) |
申请公布日期 |
2002.01.02 |
申请号 |
EP20000909465 |
申请日期 |
2000.03.10 |
申请人 |
MEDICAL RESEARCH COUNCIL;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI |
发明人 |
TSE, ERIC;RABBITS, TERENCE;CATTANEO, ANTONIO;VISINTIN, MICHELA |
分类号 |
C07K16/08;C07K16/32;C07K16/40;C12N15/10;G01N33/68;(IPC1-7):G01N33/68;C12Q1/68 |
主分类号 |
C07K16/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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