发明名称 SELECTIVE AND NON-INVASIVE VISUALIZATION OR TREATMENT OF VASCULATURE
摘要 Disclosed are methods and materials for visualizing or treating vasculature. The methods and materials in this invention relate to selective and non- invasive visualization, or treatment such as chemical occlusion, of vasculature in the mammalian eye. The methods utilize fluorescent dyes and tissue-reactive substances encapsulated within heat-sensitive liposomes whic h are subsequently heated to release the contents thereof at a predetermined anatomical locus. The methods of this invention further utilize tissue- reactive agents which, when activated, are effective to cause localized tiss ue damage and occlusion of blood vessels and/or blood sinuses. The materials of this invention relate to diagnostic reagents and kits for visualizing or treating a mammalian blood vessel or sinus.
申请公布号 CA2207624(C) 申请公布日期 2002.01.29
申请号 CA19952207624 申请日期 1995.11.16
申请人 THE JOHNS HOPKINS UNIVERSITY 发明人 ZEIMER, RAN
分类号 A61K9/127;A61K41/00;A61K45/06;A61K49/00;A61P41/00;(IPC1-7):A61K41/00;A61F9/007 主分类号 A61K9/127
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