发明名称 COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM
摘要 Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: X1-Y1-Z1-W1 (I) wherein X1 is optionally substituted aryl, optionally substituted heteroaryl or the like; Y1 is -NRACO-(CH2)0-2- or the like (wherein RA is a hydrogen or the like); Z1 is optionally substituted phenylene or the like; and W1 is a group represented by the below formula: wherein R1, R2, R3, and R4 are each independently a hydrogen atom, optionally substituted lower alkyl or the like, a broken line (---) represents the presence or absence of bond.
申请公布号 US2010022542(A1) 申请公布日期 2010.01.28
申请号 US20090504604 申请日期 2009.07.16
申请人 SHIONOGI & CO., LTD. 发明人 TAKEMOTO HIROSHI;SHIOTA TAKESHI;TAKAYAMA MASAMI
分类号 A61K31/5377;A61K31/425;A61K31/426;A61K31/427;A61K31/4439;A61P7/02;A61P43/00;C07D231/40;C07D233/88;C07D249/14;C07D277/00;C07D277/46;C07D277/82;C07D285/16;C07D285/18;C07D333/38;C07D417/02;C07D417/04;C07D417/14 主分类号 A61K31/5377
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