发明名称 |
PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF 2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYLCYTOSINE |
摘要 |
The present invention relates to a process for preparing a compound of formula 682-4, said process comprising the steps of. (i) converting a compound of formula 682-1 into a compound of formula 682-2'; (ii) converting said compound of formula 682-2' into a compound of formula 682-3; and (iii) converting said compound of formula 682-3 into a compound of formula 682-4. Further aspects of the invention relate to the use of the above process in the preparation of 2'-cyano-2'-deoxy-N4 -palmitoyl-1-.beta.-D-arabmofuranosylcytosine, a pyrimidine nucleoside which is therapeutically useful in the treatment and/or prevention of cancer. |
申请公布号 |
CA2723702(C) |
申请公布日期 |
2016.06.21 |
申请号 |
CA20092723702 |
申请日期 |
2009.05.08 |
申请人 |
CYCLACEL LIMITED |
发明人 |
WOOD, GAVIN JEFFREY;WESTWOOD, ROBERT |
分类号 |
C07F7/10;C07H19/06 |
主分类号 |
C07F7/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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