NON-STEROIDAL ANTI-INFLAMMATORY DRUG DOSAGE FORM

摘要

A non-steroidal anti-inflammatory drug (NSAID) in a single solid dosage form for the provision of a sustained therapeutic effect to a mammal, said single solid dosage form comprising an immediate release portion containing an initial dose of the non-steroidal anti-inflammatory drug and a delayed burst release portion containing a second dose of the non-steroidal anti-inflammatory drug for delivery about 3 to 5 hours after delivery of said initial dose, wherein said non-steroidal anti-inflammatory drug has a duration of therapeutic effect which lasts at least about 6 hours after delivery of said second dose, and wherein said initial dose is at least about twice of said second dose.