发明名称 (6s,9as)-n-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1h-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
摘要 A compound represented by formula (1) or pharmaceutically acceptable salt thereof: wherein R1 is a C1-6 alkyl group; R2 and R3 are the same or different from each other and each is a hydrogen atom or a C1-6 alkyl group; X2, X3 and X4 are the same or different from each other and each is a hydrogen atom or a halogen atom; and X5 is a hydrogen atom or —P(═O)(OH)2 has a Wnt Pathway modulating activity.
申请公布号 IL245961(D0) 申请公布日期 2016.08.02
申请号 IL20160245961 申请日期 2016.06.01
申请人 EISAI R& D MANAGEMENT CO. LTD.;PRISM PHARMA CO. LTD. 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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