| 摘要 |
1,2-Benxodiazine derivs. of the formula(I) [R = CH3, n-Pr, iso-Pr, n- Bu, vinyl, aryl or alkenyl! were prepd. Thus, diazonium salt of 3,4- methylenedioxyanilline(II) was reacted with Na2SO3 at 60-70≦̸C to give hydrazine(III) of II. III was reacted with diethylketomalonate to give diethylmethoxalate(IV) of II. IV was heated in diphenylether at 240-250≦̸C for 1 hr. to give 3-ethoxycarbonyl-4-OH-6,7- methylenedioxycinolline(V). V was reacted with Na2CO3 and ethyliodide in DMF at 80-90≦̸C for 8 hr and hydrolyzed in NaOH to give I. I are used as antibacterial agents.
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