摘要 |
<p>Conjugated nitro alkene compounds hamper or prevent proliferation of cancer cells in cell culture and in cancer patients, which can result in a decrease in tumor size and/or disappearance of the cancer. The compounds may act by interference with cancer cell biochemistry, in which isoprenoid groups such as farnesyl and geranylgeranyl become bonded to various oncogenic proteins such as Ras, RhoA, RhoB, or some other growth-related cellular protein(s).</p> |
申请人 |
THE ARIZONA DISEASE CONTROL RESEARCH COMMISSION;ROSE, SETH, D.;OKOLOTOWICZ, KARL, J.;HARTMAN, ROSEMARIE, F.;HOUTCHENS, JASON |
发明人 |
ROSE, SETH, D.;OKOLOTOWICZ, KARL, J.;HARTMAN, ROSEMARIE, F.;HOUTCHENS, JASON |