| 发明名称 |
POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS |
| 摘要 |
<p>The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 or a fragment thereof, S. aureus AhpC-AhpF compositions, and uses of such polypeptides and compositions. SEQ ID NO: 1 has a full length S. aureus AhpC sequence. A derivative of SEQ ID NO: 1 containing an amino His-tag and three additional carboxylamino acids was found to produce a protective immune response against S. aureus.</p> |
| 申请公布号 |
EP1843785(A2) |
申请公布日期 |
2007.10.17 |
| 申请号 |
EP20060718701 |
申请日期 |
2006.01.17 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
KELLY, ROSEMARIE;SCHULTZ, LOREN, D.;MILLER, MARK, A.;YEAGER, MARK, D.;MCNEELY, TESSIE |
| 分类号 |
A61K39/09;C07H21/02;C12N15/00;C12Q1/68;G01N33/53 |
主分类号 |
A61K39/09 |
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