USE OF A RUTHENIUM PROMOTER IN A PHOSPHINE OXIDE CARBONYLATION PROCESS

摘要

The present technology relates to a rhodium catalyzed carbonylation process of alcohols, ethers, and esters in the presence of phosphine oxide and ruthenium additives to produce carboxylic acids. In some embodiments, the technology provides for an improved method of preparing acetic acid from methyl acetate or methanol using a rhodium catalyst with a phosphine oxide and a ruthenium additive.

主权项

1. A method for producing acetic acid comprising reacting:
(A) a starting material selected from methanol, dimethyl ether, or methyl acetate; (B) carbon monoxide; and (C) a rhodium compound; in a reaction mixture in the presence of a ruthenium compound, a first iodide source, and a phosphine oxide(C≦24) under conditions sufficient to cause carbonylation to produce acetic acid.