发明名称 |
TRANSDERMALLY ABSORBABLE BASE MATERIAL COMPRISING LIPID PEPTIDE-TYPE COMPOUND |
摘要 |
[Problem] To provide a novel transdermally absorbable base material wherein a low molecular gelling agent is used so as to improve not only a use feeling but also transdermal absorbability. [Solution] A transdermally absorbable base material comprising: at least one kind of a lipid peptide-type compound selected from among a compound represented by formula (1), an analogue thereof and pharmaceutically usable salts of the same; a surfactant; a specific polyhydric alcohol; a fatty acid; and water. In formula (1): R1 represents an aliphatic group having 9-23 carbon atoms; R2 represents a hydrogen atom or an alkyl group having 1-4 carbon atoms which may have a branched chain with 1 or 2 carbon atoms; and R3 represents a -(CH2)n-X group [wherein n represents a numerical value of 1-4, and X represents an amino group, a guanidino group, a -CONH2 group, or a five-membered or six-membered ring which may have 1-3 nitrogen atoms or a fused heterocyclic ring composed of a five-membered ring and a six-membered ring]. |
申请公布号 |
WO2016121867(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016JP52488 |
申请日期 |
2016.01.28 |
申请人 |
KYUSHU UNIVERSITY;NISSAN CHEMICAL INDUSTRIES, LTD. |
发明人 |
GOTO, MASAHIRO;MIYAJI, NOBUHIDE;IWAMA, TAKEHISA;IMOTO, TAKAYUKI |
分类号 |
A61K47/42;A61K9/06;A61K47/10;A61K47/12 |
主分类号 |
A61K47/42 |
代理机构 |
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