| 摘要 |
The present invention relates to recombinant E. coli for producing fucosyllactose and to a method for producing fucosyllactose by using the same. The recombinant E. coli has one or more pulverized genes for coding fucose isomerase (FucI), fuculose kinase (FucK), and fuculose 1-phosphate aldolase (FucA), which are fucose metabolism enzymes; and contains a lac operon consisting of a lacZ gene, a wild-type lacY gene, and a wild-type lacA gene for coding beta-galactosidase having a lower activity than wild-type beta-galactosidase, or a lac operon consisting of only a wild-type lacY gene and a wild-type lacA gene without a wild-type lacZ gene, instead of a wild-type lac operon. According to the present invention, 2- or 3-fucosyllactose can be produced at high productivity. |
