CHRYSIN DERIVATIVES AND HYPOGLYCEMIC COMPOSITION CONTAINING THE SAME

摘要

PURPOSE: The chrysin derivatives and a hypoglycemic composition containing the compounds are provided, thereby the novel medicines containing the chrysin composition can be developed for falling blood sugar without side effects. CONSTITUTION: The chrysin is a flavonoid plant having hydroxyl group at C5 and C7 sites and has anti-oxidant, anti-inflammatory, anti-cancer and anti-allergic properties. The chrysin derivatives are represented by formula (1), in which R1 is hydrogen or propyl, R2 is propyl, butyl, octyl or toluic. The hypoglycemic composition contains the chrysin derivatives in an amount of 100 to 1000 mg/day, preferably 200 to 400 mg/day or in an amount of 1/2, 1/3, 1/4, 1/5 or 1/6 of the above amount and may be administrated to a patient suffering from diabetes 1 to six times a day.