发明名称 |
Systems and methods for detecting a substance in bodily fluid |
摘要 |
Various devices, systems and methods for determining a parameter of and/or detecting chemical and biological substances in bodily fluid are described herein. A device or system may include a substrate. An active sensor having an electrical characteristic and/or a control sensor may be disposed on the substrate. In certain variations, a differential between a first signal from the active sensor, and a second signal from the control sensor may be used to determine a parameter of the chemical or biological substance in the sample of bodily fluid. |
申请公布号 |
US9377456(B1) |
申请公布日期 |
2016.06.28 |
申请号 |
US201514599190 |
申请日期 |
2015.01.16 |
申请人 |
Avails Medical, Inc. |
发明人 |
Herget Meike;Knopfmacher Oren S. |
分类号 |
G01N15/06;G01N33/00;G01N33/48;G01N33/543 |
主分类号 |
G01N15/06 |
代理机构 |
Levine Bagade Han LLP |
代理人 |
Levine Bagade Han LLP |
主权项 |
1. A method for determining a parameter of a substance in a test sample, the method comprising:
providing a substrate having an active sensor covered in a first layer and having a first electrical component, wherein the active sensor comprises at least one functionalized structure in electrical communication with the active sensor and wherein a control sensor comprises a second electrical component having an electrical characteristic, where the functionalized structure includes a binding receptor having a functional group coupled thereto such that the functional group secures the binding receptor to the functionalized structure without the need of an adhesion layer to minimize a distance between a surface of the functionalized structure and the active sensor; binding the substance to the functionalized structure, wherein after binding, the functionalized structure affects the first electrical component to produce a changed electrical characteristic, where the changed electrical characteristic varies from the electrical characteristic; determining a comparison between the electrical characteristic and the changed electrical characteristic; using the comparison to determine at least one parameter of substance in the test sample; and producing an output of the at least one parameter. |
地址 |
Palo Alto CA US |