| 发明名称 |
TOOLS AND METHODS USING MIRNA 182, 96 AND/OR 183 FOR TREATING PATHOLOGIES |
| 摘要 |
The present inventions relates to isolated nucleic acid molecules comprising a nucleotide sequence coding for mi RNA-182 (uuuggcaaugguagaacucacacu or ugguucuagacuugccaacua), miRNA-96 (uuuggcacuagcacauuuuugcu or aaucaugugcagugccaauaug) and/or mi RNA-183 (uauggcacugguagaauucacu or gugaauuaccgaagggccauaa) for use in treating or ameliorating a ciliopathy and/or a photoreceptor dysfunction. |
| 申请公布号 |
US2016304865(A1) |
申请公布日期 |
2016.10.20 |
| 申请号 |
US201415024289 |
申请日期 |
2014.09.25 |
| 申请人 |
BUSSKAMP Volker;FILLIPOWICZ Witold;KROL Jacek;ROSKA Botond;Friedrich Miescher Institute for Biomedical Research |
发明人 |
Busskamp Volker;Filipowicz Witold;Krol Jacek;Roska Botond |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. An isolated nucleic acid molecule comprising a nucleotide sequence coding for miRNA-182 (uuuggcaaugguagaacucacacu, SEQ ID NO:1, or ugguucuagacuugccaacua, SEQ ID NO:2), miRNA-96 (uuuggcacuagcacauuuuugcu, SEQ ID NO:5, or aaucaugugcagugccaauaug, SEQ ID NO:6) and/or miRNA-183 (uauggcacugguagaauucacu, SEQ ID NO:3, or gugaauuaccgaagggccauaa, SEQ ID NO:4) for use in treating or ameliorating a ciliopathy. |
| 地址 |
Newton MA US |
