发明名称 |
Process for preparing 1,4,8,11-tetraazacyclotetradecane |
摘要 |
An improved process for preparing 1,4,8,11-tetraazacyclotetradecane comprising the tetratosylation of an acyclic tetraamine to obtain a tetratoluenesulfonamide compound in a first step, the cyclization of said sulfonamide compound to obtain tetratosyl cyclam in a second step, and the detosylation of tetratosyl cyclam in a third step followed by basification to obtain the desired 1,4,8,11-tetraazacyclotetradecane.
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申请公布号 |
US5608061(A) |
申请公布日期 |
1997.03.04 |
申请号 |
US19950510207 |
申请日期 |
1995.08.02 |
申请人 |
JOHNSON MATTHEY PLC |
发明人 |
CISZEWSKI, LECH;AMEDIO, JOHN;KAPA, PRASAD;KUCEROVY, ANDREW;LEE, GEORGE T. |
分类号 |
C07D257/02;(IPC1-7):C07D255/02 |
主分类号 |
C07D257/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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