发明名称 Novel fluorinated organic compounds, ophthalmological applications thereof and method for making same
摘要 PCT No. PCT/FR95/01131 Sec. 371 Date Feb. 26, 1998 Sec. 102(e) Date Feb. 26, 1998 PCT Filed Aug. 29, 1995 PCT Pub. No. WO97/08118 PCT Pub. Date Mar. 6, 1997The invention relates to novel fluorinated organic compounds having the following molecular structure: where RF is a fluorinated carbon chain, R1H is hydrogen or a saturated hydrogenated carbon chain, R2H is hydrogen or a saturated hydrogenated carbon chain, R1H and R2H being not simultaneously hydrogen, the group comprising a principal chain and at least one linear or cyclic branch. These compounds may be prepared by reacting a phosphine with a halide under heating, and then hot reacting in a solvent the resulting phosphonium salt with a branched aldehyde or a ketone. These compounds have an excellent stability, a good biocompatibility and a high capacity to solubilize gases and particularly oxygen, such properties allowing their use in applications of the ophthalmological type or as an organ preservation medium.
申请公布号 AU3261395(A) 申请公布日期 1997.03.19
申请号 AU19950032613 申请日期 1995.08.29
申请人 OPSIA 发明人 ISABELLE LATTES;BERNARD FEURER;BRIGITTE GUIDETTI;VIVIANE PAYROU
分类号 C07C17/263;A01N1/02;C07C17/26;C07C17/38;C07C21/18;C07F9/54 主分类号 C07C17/263
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