IMPFSTOFF AUS REASSORTIERTEM ROTAVIRUS

摘要

The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. The reassortant contains the gene encoding the v.p.4 neutralization antigen of a selected human rotavirus and/or the gene encoding the v.p.7 neutralization antigen of a selected human rotavirus, with remaining genes being provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.