发明名称 |
Enhanced purification and expression of insoluble recombinant proteins |
摘要 |
Protein aggregates obtained by a process comprising culturing a host cell that expresses a desired protein in a medium comprising an effective amount of Cu++ and wherein the desired protein forms inclusion bodies in the host cell.
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申请公布号 |
US5866362(A) |
申请公布日期 |
1999.02.02 |
申请号 |
US19950477454 |
申请日期 |
1995.06.07 |
申请人 |
CHIRON CORPORATION |
发明人 |
COUSENS, LAWRENCE S.;TEKAMP-OLSON, PATRICIA |
分类号 |
A61K48/00;C07K1/113;C07K14/155;C07K14/16;C07K14/18;C07K14/53;C07K14/55;C07K14/565;C07K14/62;C07K14/65;C12N1/15;C12N9/02;C12N15/81;C12N15/85;C12N15/88;C12N15/90;C12P21/02;(IPC1-7):C12N5/00;C12N1/20;C12P21/04;C12P1/20 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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