CONVERSION OF NATURALLY-OCCURRING QUINONES TO QUINONE DERIVATIVES BY MACROPHAGE MIGRATION INHIBITION FACTOR AND USES THEREOF
摘要
The present invention provides methods of using a protein of the macrophage migration inhibitory factor family to promote conversion of a naturally-occurring toxic quinone to a less toxic quinone derivative, thereby detoxifying the naturally-occurring quinone and preventing cell death. The present invention also provides methods of diagnosis, prevention, and treatment of degenerative disorders characterized by quinone-induced cell death.
申请公布号
WO0006189(A2)
申请公布日期
2000.02.10
申请号
WO1999US17057
申请日期
1999.07.27
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;WISTOW, GRAEME, J.;HEARING, VINCENT, J.;SOLANO, FRANCISCO
发明人
WISTOW, GRAEME, J.;HEARING, VINCENT, J.;SOLANO, FRANCISCO
