| 发明名称 |
SOLUBLE HETERODIMERIC CYTOKINE RECEPTORS |
| 摘要 |
A soluble receptor that binds to IL-20 having two polypeptide subunits, IL-22R and IL-20RB. The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.
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| 申请公布号 |
EA005496(B1) |
申请公布日期 |
2005.02.24 |
| 申请号 |
EA20030000983 |
申请日期 |
2002.03.07 |
| 申请人 |
ZYMOGENETICS, INC. |
发明人 |
CHANDRASEKHER, YASMIN, A.;NOVAK, JULIA;FOSTER, DONALD, C.;XU, WENFENG;JASPERS, STEPHEN, R. |
| 分类号 |
C12N15/09;A61K38/00;A61P11/00;A61P17/06;A61P29/00;C07K14/715;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;(IPC1-7):C07K14/00;C07K16/00;C12N15/00 |
主分类号 |
C12N15/09 |
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