OXIME DERIVATIVE

摘要

Disclosed is an oxime derivative represented by the formula below or a pharmacologically acceptable salt thereof, which is a novel compound having an excellent glucokinase activation effect and therefore useful as an active ingredient of a pharmaceutical agent for the prevention and/or treatment of a glucokinase-related disease such as diabetes, diabetic complication or obesity. wherein the ring A represents an aryl group or a heteroaryl group; Q represents a cycloalkyl group, a heterocyclic group or the like; the ring T represents a heteroaryl group or a heterocyclic group; R<SUP>1</SUP> represents a hydrogen atom or the like; R<SUP>2</SUP> represents -COR<SUP>11</SUP> or -CR<SUP>13</SUP>(OH)R<SUP>11</SUP>; R<SUP>11</SUP> represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group or the like; R<SUP>13</SUP> represents a hydrogen atom or an alkyl group; R<SUP>3</SUP> and R<SUP>4</SUP> independently represent a hydrogen atom, an alkoxy group or the like; R<SUP>5</SUP> represents a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkyl group or the like; and R<SUP>6</SUP> represents a hydrogen atom or the like.