| 发明名称 |
COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR |
| 摘要 |
The present invention provides a screening assay for identifying inhibitors of Pseudomonas aeruginosa CFTR Inhibitory Factor as well as compositions and methods for ameliorating or treating a respiratory disease such as cystic fibrosis or secondary infection thereof. |
| 申请公布号 |
US2016206605(A1) |
申请公布日期 |
2016.07.21 |
| 申请号 |
US201514982298 |
申请日期 |
2015.12.29 |
| 申请人 |
TRUSTEES OF DARTMOUTH COLLEGE ;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
Madden Dean R.;Bahl Christopher D.;Hammock Bruce D.;Morisseau Christophe |
| 分类号 |
A61K31/445;A61K31/192;A61K31/198;A61K31/336;A61K31/17;A61K31/415;C12Q1/34;A61K9/00;A61K31/085 |
主分类号 |
A61K31/445 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition formulated for pulmonary administration comprising an inhibitor of Cystic fibrosis transmembrane conductance regulator Inhibitory Factor (Cif) activity in admixture with a pharmaceutically acceptable carrier. |
| 地址 |
HANOVER NH US |
