| 发明名称 |
FORAZOLINES, COMPOSITIONS THEREOF AND USES THEREOF |
| 摘要 |
An isolated compound of Formula I and salts thereof are provided:;;wherein X is Cl or Br. A compound isolated from Actinomadura and having a chemical formula of C43H69ClN4O10S2 or C43H69BrN4O10S2 is also provided. Compositions including the compounds and methods of using the compounds to treat fungal infections including those such as Candida are also disclosed. |
| 申请公布号 |
US2016243089(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201615146672 |
申请日期 |
2016.05.04 |
| 申请人 |
Wisconsin Alumni Research Foundation |
发明人 |
BUGNI Timothy;WYCHE Thomas;ANDES David;BRAUN Douglas |
| 分类号 |
A61K31/429;A61K45/06 |
主分类号 |
A61K31/429 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising an effective amount of a compound of Formula I: or pharmaceutically acceptable salt thereof for treating a fungal infection in a mammal, wherein X is Cl or Br; and a pharmaceutically acceptable carrier. |
| 地址 |
Madison WI US |
