| 发明名称 |
PYRIDONE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF TUBERCULOSIS |
| 摘要 |
A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the inhibition of mycolic acid biosynthesis through inhibition of M. tuberculosis Enoyl Acyl Carrier Protein Reductase enzyme (InhA): wherein R1, R2, R3, R4 and R5 are as defined herein. |
| 申请公布号 |
EP2931716(B1) |
申请公布日期 |
2016.11.02 |
| 申请号 |
EP20130814360 |
申请日期 |
2013.12.12 |
| 申请人 |
NOVARTIS AG |
发明人 |
KONDREDDI, RAVINDER REDDY;UJJINI, MANJUNATHA H.;MA, NGAI, LING;PEUKERT, STEFAN;RAO, SRINIVASA P S |
| 分类号 |
C07D213/64;A61K31/4412;A61K31/4433;A61K31/444;A61P31/06;C07D213/69;C07D401/04;C07D401/06;C07D405/06 |
主分类号 |
C07D213/64 |
| 代理机构 |
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