发明名称 |
Substrate Trapping Protein Tyrosine Phosphatases |
摘要 |
Novel protein tyrosine phosphatases in which the invariant aspartate residue is replaced with an alanine residue and which bind to a tyrosine phosphorylated substrate and are catalytically attenuated are described. Also described are methods of identifying tyrosine phosphorylated proteins which complex with the described protein tyrosine phosphatases. |
申请公布号 |
AU5939598(A) |
申请公布日期 |
1999.02.16 |
申请号 |
AU19980059395 |
申请日期 |
1997.07.24 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
NICHOLAS TONKS;ANDREW J. FLINT |
分类号 |
C12N15/09;A61K38/00;A61K38/46;A61P35/00;C12N9/12;C12N9/16;C12Q1/42 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|