摘要 |
Provided are: a modified host cell formed by introducing into a micro-organism host cell a polynucleotide that codes tRNA having a high usage frequency relative to the amount supplied; a method for manufacturing said modified host cell; a nucleic acid molecule containing said polynucleotide for modifying the host cell; a vector and kit; and a method for using the polynucleotide to improve the yield of a substance from a micro-organism. The introduction of the gene that codes the tRNA having a high usage frequency makes it possible to increase the expression of proteins in the micro-organism host cells. |