发明名称 |
NUCLEIC ACID CONSTRUCT |
摘要 |
The present invention provides a nucleic acid construct comprising the following structure: A – X – B in which A is nucleic acid sequence encoding a first polypeptide which comprises a first signal peptide; B is nucleic acid sequence encoding a second polypeptide which comprises a second signal peptide and X is a nucleic acid sequence which encodes a cleavage site, wherein the first signal peptide or the second signal peptide comprises one or more mutation(s) such that it has fewer hydrophobic amino acids. |
申请公布号 |
WO2016174409(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
WO2016GB51165 |
申请日期 |
2016.04.26 |
申请人 |
UCL BUSINESS PLC |
发明人 |
PULÉ, Martin;CORDOBA, Shaun |
分类号 |
A61K39/00;C07K16/28;C12N5/0783 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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