发明名称 |
QUATERNARY AMMONIUM SALTS AND THEIR USE AS ANTI-HIV AGENTS |
摘要 |
<p>This invention is to provide a compound for antagonizing CCR5, said compound being represented by formula (I), wherein R<1> is an optionally substituted phenyl or an optionally substituted thienyl; Y is -CH2-, -S- or -O-; and R<2>, R<3> and R<4> are independently an optionally substituted aliphatic hydrocarbon group or an optionally substituted alicyclic heterocyclic ring group, and being effective for the prevention and treatment of infectious disease of HIV.</p> |
申请公布号 |
WO0010965(A3) |
申请公布日期 |
2000.06.29 |
申请号 |
WO1999JP04454 |
申请日期 |
1999.08.19 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SHIRAISHI, MITSURU;BABA, MASANORI;ARAMAKI, YOSHIO;NISHIMURA, OSAMU;KANZAKI, NAOYUKI |
分类号 |
C07D313/08;A61K31/00;A61K31/167;A61K31/335;A61K31/351;A61K31/452;A61K31/4523;A61K31/5377;A61K31/55;A61K31/665;A61K31/67;A61K31/76;A61K45/06;A61P31/00;A61P31/12;C07C233/62;C07D309/14;C07D337/08;C07D407/12;(IPC1-7):C07D337/08;C07D409/12;A61P31/18 |
主分类号 |
C07D313/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|