发明名称 Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
摘要 Pharmaceutical compositions are disclosed suitable for parenteral administration having anti-inflammatory, analgesic, and anti-pyretic properties, which consist of a therapeutically effective amount of d,l or l-lysine salt of R,S or S-ibuprofen as active ingredient dissolved in sterile water to form a solution in the absence of an inert atmosphere and either substantially free or absolutely free of any excipient, organic solvent, buffer, acid, base, salt other than the active ingredient and capable of storage in the absence of an inert atmosphere. Also disclosed are methods employing the new compositions in the treatment of pain and inflammation, in reducing fever and in treating patent ductus arterious or intraventricular hemorrhage in prematurely born neonates.
申请公布号 US6342530(B1) 申请公布日期 2002.01.29
申请号 US20000712430 申请日期 2000.11.14
申请人 FARMACON-IL, LLC 发明人 DARKO LASZLO
分类号 A61K9/08;A61K31/192;A61K31/195;A61K47/18;A61P9/00;A61P13/12;A61P29/00;(IPC1-7):A61K31/195 主分类号 A61K9/08
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