THIEPINO[3,2-b]DIHYDROPYRIDINES AND RELATED COMPOSITIONS AND METHODS

摘要

THIS INVENTION PROVIDES NOVEL THIEPINO [3,2-b] DIHYDROPYRIDINES OF THE FOLLOWING FORMULAE: THESE COMPOUNDS ARE USEFUL AS CALCIUM CHANNEL ANTAGONISTS WITH CARDIOVASCULAR, ANTIASTHMATIC AND ANTIBRONCHOCONSTRICTION ACTIVITY. THUS, THIS INVENTION ALSO PROVIDES PHARMACEUTICAL COMPOSITIONS, AS WELL AS METHODS, FOR PREVENTING AND TREATING DISORDERS SUCH AS HYPERSENSITIVITY, ALLERGY, ASTHMA,BRONCHOSPASM, DYSMENORRHEA SPASM, GLAUCOMA, PREMATURE LABOR, URINARY TRACT DISORDERS , GASTROINTESTINAL MOTILITY DISORDERS AND CARDIOVASCULAR DISORDERS.