| 摘要 |
<p>The present invention relates to (hetero)aryl compounds of general formula (I) wherein the groups and radicals A, B, Q, W, X, Y, Z, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4a</SUP>, R<SUP>4b</SUP>, R<SUP>5a</SUP>, R<SUP>5b</SUP>, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to 10 the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.</p> |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG;ROTH, GERALD JUERGEN;MUELLER, STEPHAN GEORG;LEHMANN-LINTZ, THORSTEN;STENKAMP, DIRK;LUSTENBERGER, PHILIPP;KLEY, JOERG;RUDOLF, KLAUS;HECKEL, ARMIN;SCHINDLER, MARCUS;THOMAS, LEO;LOTZ, RALF R. H. |
发明人 |
ROTH, GERALD JUERGEN;MUELLER, STEPHAN GEORG;LEHMANN-LINTZ, THORSTEN;STENKAMP, DIRK;LUSTENBERGER, PHILIPP;KLEY, JOERG;RUDOLF, KLAUS;HECKEL, ARMIN;SCHINDLER, MARCUS;THOMAS, LEO;LOTZ, RALF R. H. |
