发明名称 |
METHOD FOR THE SYNTHESIS OF SUCROSE-6-ESTERS |
摘要 |
<p>The present application discloses a process for the synthesis of a sucrose-6-ester comprising: (a) forming a first reaction mixture comprising sucrose, a polar aprotic solvent, and an organotin-based acylation promoter; (b) removal of water from said first reaction mixture by contacting, in a continuous counter-current manner, with gas or solvent vapour capable of removing water at a temperature, pressure and residence time sufficient to afford a second reaction mixture which is substantially free from water; followed by (c) adding a carboxylic anhydride to said second reaction mixture to afford a third reaction mixture, and maintaining said third reaction mixture at a temperature and for a period of time sufficient to produce a sucrose-6-ester. The sucrose-6-ester can be used to make sucralose.</p> |
申请公布号 |
WO2008084197(A1) |
申请公布日期 |
2008.07.17 |
申请号 |
WO2008GB00013 |
申请日期 |
2008.01.04 |
申请人 |
TATE & LYLE TECHNOLOGY LIMITED;BOUTZALE, WAYNE, N.;MICINSKI, EDWARD |
发明人 |
BOUTZALE, WAYNE, N.;MICINSKI, EDWARD |
分类号 |
C07H1/00;C07H13/04 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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