| 摘要 |
Disclosed is a method for producing a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin cleavage products. Said method is characterized in that the impurities are precipitated using a non-denaturing precipitating agent at a temperature ranging from -4° to +4° C and a Ca ion activity which does not exceed that of a 1,000 µM CaCl2 solution and are separated from the solution by means of a filtering or centrifugation process. |
