SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES

摘要

Disclosed herein are processes for forming 2-furoic acid derivatives represented by Formula (I):;

主权项

1. A process for preparing a compound of Formula (I)comprising:
converting a compound of Formula (II) to an intermediate compound of Formula (III):and
saponifying the intermediate compound of Formula (III) to form the compound of Formula (I),wherein,
R1 is alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroarylalkyl, heterocyclyl or heterocyclylalkyl; R2 is C1-4 alkyl; and X is halo.