| 发明名称 |
Anti-GP73 monoclonal antibodies and methods of obtaining the same |
| 摘要 |
Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample. |
| 申请公布号 |
US9469686(B2) |
申请公布日期 |
2016.10.18 |
| 申请号 |
US201313836229 |
申请日期 |
2013.03.15 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
Tu Bailin;Ziemann Robert N.;Tieman Bryan C.;Hemken Philip M.;Ramsay Carol S.;Strobel Carolyn J.;Hawksworth David J.;Birkenmeyer Larry G.;Zhao Cheng;Brophy Susan E.;Dowell Barry L.;Muerhoff Anthony S. |
| 分类号 |
C07K16/00;A61K39/395;C07K16/18;G01N33/574;G01N33/68 |
主分类号 |
C07K16/00 |
| 代理机构 |
|
代理人 |
Reininger Irene M. |
| 主权项 |
1. An isolated antibody which binds to Golgi Protein 73 (“GP73”), wherein the antibody comprises a variable heavy domain chain comprising a CDR1 comprising the amino acid sequence of SEQ ID NO:42, a CDR2 comprising the amino acid sequence of SEQ ID NO:43, and a CDR comprising the amino acid sequence of SEQ ID NO:44, and a variable light domain chain comprising a CDR1 comprising the amino acid sequence of SEQ ID NO:46, a CDR2 comprising the amino acid sequence of SEQ ID NO:47, and a CDR3 comprising the amino acid sequence of SEQ ID NO:48. |
| 地址 |
Abbott Park IL US |
