| 发明名称 | Salt crystals | ||
| 摘要 | The present invention relates to acid addition salt and salt crystals of (6aR,9aS)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluoropyridin-2-yl)phenyl)methyl)-cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one, composition comprising the same and the method of making and using such salt and crystal. | ||
| 申请公布号 | US9469647(B2) | 申请公布日期 | 2016.10.18 |
| 申请号 | US201314409988 | 申请日期 | 2013.06.21 |
| 申请人 | INTRA-CELLULAR THERAPIES, INC. | 发明人 | Li Peng;Wennogle Lawrence P.;Davis Robert;Buckton Graham;Hooper Mark |
| 分类号 | C07D487/14;A61K31/519;A61P35/00;C07C55/02;C07C57/15;C07C309/04 | 主分类号 | C07D487/14 |
| 代理机构 | Hoxie & Associates LLC | 代理人 | Hoxie & Associates LLC |
| 主权项 | 1. The compound (6aR,9aS)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluoropyridin-2-yl)phenyl)methyl)-cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one in an acid addition salt form selected from fumarate, hydrochloride, (1-hydrox-2)-naphthoate, benzosulfonate, phosphate, mesylate, tartrate, sulphate and hydrobromate. | ||
| 地址 | New York unknown | ||