| 发明名称 | Aminocyclobutane derivatives, method for preparing same and the use thereof as drugs | ||
| 摘要 | The present inventions concerns derivatives of aminocyclobutane, particularly as NMDA receptor antagonists, their application in human therapy and their method of preparation.;These compounds correspond to the general formula (1):; wherein: X1 represents a hydrogen atom or fluorine atom;X2 is a hydrogen atom or fluorine atom or chlorine atom;R1 represents a hydrogen atom or fluorine atom or chlorine atom or methyl group or methoxy group or cyano group;R2 represents independently or together a methyl group or ethyl group. | ||
| 申请公布号 | US9469601(B2) | 申请公布日期 | 2016.10.18 |
| 申请号 | US201314649448 | 申请日期 | 2013.12.04 |
| 申请人 | PIERRE FABRE MEDICAMENT | 发明人 | Vacher Bernard;Blanc Elodie;Depoortere Ronan |
| 分类号 | A01N31/16;A61K31/165;C07C235/40;C07C231/14;C07C237/24;C07D307/00 | 主分类号 | A01N31/16 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. Compound of the following general formula (1): or pharmaceutically acceptable salt or solvate thereof, wherein: X1 represents a hydrogen atom or fluorine atom;X2 is a hydrogen atom or fluorine atom or chlorine atom;R1 represents a hydrogen atom or fluorine atom or chlorine atom or methyl group or methoxy group or cyano group; andR2 represents independently or together a methyl group or ethyl group. | ||
| 地址 | Boulogne-Billancourt FR | ||