| 摘要 |
Disclosed herein is a method for treating and preventing prostate cancer, the method comprising administering to a mammal a benzothiopene having the formula (I) or pharmaceutically acceptable salts thereof, wherein R and R1 are each independently selected from the group consisting of hydrogen, -COR2, -COR3, and R4; R2 is selected from the group consisting of hydrogen, C1-C14 alkyl, C-C3 chloroalkyl, C1-C3 fluoroalkyl, C5-C7 cycloalkyl, C1-C4 alkoxy, and phenyl; R3 is phenyl with at least one substitution selected from the group consisting of C1-C4 alkyl C1-C4 alkoxy, hydroxy, nitro, chloro, fluoro, trichloromethyl, and trifluoromethyl; R4 is selected from the group consisting of C1-C4 alkyl, C5-C7 cycloalkyl, and benzyl; and R5 is selected from the group consisting of oxygen and C=O.
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