发明名称 |
MULTILAMELLAR LIPID VESICLE COMPOSITIONS INCLUDING A CONJUGATED ANAPLASTIC LYMPHOMA KINASE (ALK) VARIANT AND USES THEREOF |
摘要 |
The invention provides compositions including stabilized multilamellar lipid vesicles having crosslinked lipid bilayers (referred to herein as interbilayer-crosslinked multilamellar vesicles or ICMV) and including an ALK variant, pharmaceutical compositions containing vesicles (e.g., ICMV) including an ALK variant, and methods of treatment using such compositions. The invention provides compositions including stabilized multilamellar lipid vesicles with crosslinked lipid bilayers (e.g., an interbilayer-crosslinked multilamellar vesicle or ICMV) containing an Anaplastic lymphoma kinase (ALK) variant as an antigen that is associated with solid tumor cancers. |
申请公布号 |
WO2016115480(A1) |
申请公布日期 |
2016.07.21 |
申请号 |
WO2016US13635 |
申请日期 |
2016.01.15 |
申请人 |
VEDANTRA PHARMACEUTICALS, INC. |
发明人 |
LI, ADRIENNE;EBY, JACKSON;DEMUTH, PETER, C. |
分类号 |
A61K39/395;A61K9/127 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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