发明名称 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY
摘要 Compounds of general formula (I): in which: R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB> and FG are as defined in the specification and claims, optionally conjugated with a suitable molecule able to interact with physiological systems; and their chelates with bi-trivalent ions of the metal elements having atomic number ranging between 20 and 31, 39, 42, 43, 44, 49, and between 57 and 83, and radioisotopes, as well as the salts thereof with physiologically compatible bases or acids.
申请公布号 WO2006136564(A9) 申请公布日期 2008.02.07
申请号 WO2006EP63368 申请日期 2006.06.20
申请人 BRACCO IMAGING S.P.A.;GIOVENZANA, GIOVANNI, BATTISTA;PALMISANO, GIOVANNI;SISTI, MASSIMO;CAVALLOTTI, CAMILLA;AIME, SILVIO;CALABI, LUISELLA;SWENSON, ROLF;KONDAREDDIAR, RAMALINGAM;LATTUADA, LUCIANO;MOROSINI, PIERFRANCESCO 发明人 GIOVENZANA, GIOVANNI, BATTISTA;PALMISANO, GIOVANNI;SISTI, MASSIMO;CAVALLOTTI, CAMILLA;AIME, SILVIO;CALABI, LUISELLA;SWENSON, ROLF;KONDAREDDIAR, RAMALINGAM;LATTUADA, LUCIANO;MOROSINI, PIERFRANCESCO
分类号 C07D243/08;A61K49/00;A61K49/10;A61K49/14;A61K51/00;A61P35/00;C07C229/16;C07C229/26;C07D243/14;C07D245/02;C07F1/08;C07F1/10;C07F1/12;C07F5/00;C07F7/24;C07F9/38;C07F9/645;C07F9/80;C07F9/94;C07F11/00;C07F13/00;C07F15/00;C07F15/02 主分类号 C07D243/08
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