Pyrimidine derivative as P13K inhibitor and use thereof

摘要

Disclosed is a medical agent which is excellent in stability in living bodies and water solubility, while having excellent PI3K inhibitory activity. The medical agent is thus useful for prevention or treatment of cancers. Specifically disclosed is a compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof. (I) In the formula, X represents a single bond or the like; Y represents a single bond or the like (provided that X and Y are not single bonds at the same time); Z represents a hydrogen atom or the like; m represents an integer of 1 or 2; and R<1> represents a cyclic substituent.