发明名称 |
Inhibition of Mac-1 receptor binding to fibrinogen using D30 homologs |
摘要 |
The present invention contemplates therapeutic compositions containing a D30 homolog capable of binding to the Mac-1 receptor D30 binding site and inhibiting fibrinogen binding to the Mac-1 receptor via the D30 binding site, Methods of inhibiting Mac-1 receptor binding to any Mac-1 ligand and methods of inhibiting Mac-1 receptor mediated inflammation within a patient by administering a D30 homolog are also contemplated,
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申请公布号 |
US5473051(A) |
申请公布日期 |
1995.12.05 |
申请号 |
US19910734296 |
申请日期 |
1991.07.18 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ALTIERI, DARIO C.;PLOW, EDWARD F.;EDGINGTON, THOMAS S. |
分类号 |
A61K38/00;A61K38/36;A61K39/395;C07K7/06;C07K7/08;C07K14/00;C07K14/705;C07K14/75;C07K16/00;C07K16/36;C07K16/42;C12N15/02;C12N15/12;C12P21/06;C12P21/08;C12R1/91;G01N33/53;G01N33/566;G01N33/577;(IPC1-7):C07K14/75 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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